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Old 04-06-2021, 12:15 PM   #8661
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Huh, yeah, this study seems to suggest that a staple (no pun intended) of coronaviruses in general is the S-glycoprotein viral spike. It’s from all the way back to 2003.

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Old 04-06-2021, 12:23 PM   #8662
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Hmm, you sure about that? Per this study MERS does utilize a spike protein, though I’m now sure how it may differ. Looking at SARS now, but keep getting SAR-CoV hits so it’s hard to validate.

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The spike protein was in SARS, however it didn’t have the ability to attach to our ACE2 cells. I misspoke, you’re correct.
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Old 04-06-2021, 12:26 PM   #8663
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Uhh, I have some news for you...

Oh god, what did I miss?
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Old 04-06-2021, 12:53 PM   #8664
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The spike protein was in SARS, however it didnít have the ability to attach to our ACE2 cells. I misspoke, youíre correct.
Yup, they all seem to enter different cells, but they enter using the same ďtoolĒ (that spike protein). Funny enough, I found a study done in 2019 that cautioned that significant mutations in spike proteins for MERS patients could threaten the efficacy of previous antibodies, but the mutations - even though they threatened to bypass antibodies - also caused the virus itself to weaken and seemingly become less effective (if I was interpreting it correctly, itís pretty dense shit).

Let me see if I can dig it back up.

Virology and immunology - both - are so strange.
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Old 04-06-2021, 06:27 PM   #8665
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Our province isn't going to start vaccinating essential workers until sometime in May?
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Old 04-06-2021, 07:28 PM   #8666
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I can get my J&J tomorrow or moderna on friday (and then the 7th). Dilemma, dilemma, dilemma.
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Old 04-06-2021, 08:33 PM   #8667
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I can get my J&J tomorrow or moderna on friday (and then the 7th). Dilemma, dilemma, dilemma.
Get Moderna. J&J is only 10% effective against one of the strains. mRNA> Viral Vector.
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Old 04-07-2021, 05:33 AM   #8668
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Our province isn't going to start vaccinating essential workers until sometime in May?
See, this is what Iím talking about with blaming individual politicians for rollout issues. I would never blame Trudeau for that, honestly who knows whoís to blame, there are a million different circumstances that can affect supply chain that have nothing to do with politicians.

But in America, everyone jumped to blame Trump. And now when some places hit a snag some blame Biden. Itís all nonsense, and I hate politicians, but you simply arenít rooted in the real world if you think any hiccups during a global pandemic are THEIR FAULT.

Hopefully things pick up, Gweeps. I love and miss Canada and am dying to take a trip up there. Iíve actually been thinking about doing a cross-Canada road trip sometime in the next 2-3 years.
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Old 04-07-2021, 06:33 AM   #8669
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Our province isn't going to start vaccinating essential workers until sometime in May?
any news if Canada is going to 'require' a vaccinated person to enter the country?
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Old 04-07-2021, 09:23 AM   #8670
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[Only registered users can see links.] found that one-third of patients who suffered severe bouts of the coronavirus were then diagnosed with a mental health condition.

Utilizing the electronic health records of 236,379 patients, a majority of whom were from the United States, researchers found that 34 percent were attributed with a neurological or psychiatric disorder.
All the more reason to take stricter measures to [Only registered users can see links.] .
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Old 04-07-2021, 09:32 AM   #8671
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[Only registered users can see links.] found that one-third of patients who suffered severe bouts of the coronavirus were then diagnosed with a mental health condition.

Utilizing the electronic health records of 236,379 patients, a majority of whom were from the United States, researchers found that 34 percent were attributed with a neurological or psychiatric disorder.
All the more reason to take stricter measures to [Only registered users can see links.] .
but what about the mental health issues of those who have been under the stricter measures. I wound find it hard to believe that the number there is 'smaller' than 'one-third of patients who suffered severe bouts of coronavirus'. just food for thought, there are other people suffering who do not contract the virus.
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Old 04-07-2021, 10:21 AM   #8672
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but what about the mental health issues of those who have been under the stricter measures. I wound find it hard to believe that the number there is 'smaller' than 'one-third of patients who suffered severe bouts of coronavirus'. just food for thought, there are other people suffering who do not contract the virus.
Apples and oranges.

the whole COVID-19 cohort had estimated incidences of

0∑56% for intracranial haemorrhage
2∑10% for ischaemic stroke
0∑11% for parkinsonism
0∑67% for dementia
17∑39% for anxiety disorder, and

1∑40% for psychotic disorder, among others.
We're not talking about depression here.
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Old 04-07-2021, 10:32 AM   #8673
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Apples and oranges.

the whole COVID-19 cohort had estimated incidences of

0∑56% for intracranial haemorrhage
2∑10% for ischaemic stroke
0∑11% for parkinsonism
0∑67% for dementia
17∑39% for anxiety disorder, and

1∑40% for psychotic disorder, among others.
We're not talking about depression here.
17-39% anxiety disorder, isn't that just fancy for depression? I see your point, it is a bit apples and oranges, however I still stand by mine.
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Old 04-07-2021, 12:28 PM   #8674
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The reason covid can cause mental issues is because it breaks the BBB. You can actually have virus on/in your brain.
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Old 04-07-2021, 12:55 PM   #8675
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Get Moderna. J&J is only 10% effective against one of the strains. mRNA> Viral Vector.


Cancelled the J&J. Going to ride or die with Moderna. Wanted Pfizer though.
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Old 04-07-2021, 01:01 PM   #8676
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So there is a small chance of blood clots with AstraZeneca. Can't live without risk!
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Old 04-07-2021, 01:14 PM   #8677
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:Upyours

Cancelled the J&J. Going to ride or die with Moderna. Wanted Pfizer though.


I think with either Pfizer or Moderna, you're good to go.
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Old 04-07-2021, 01:32 PM   #8678
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I think with either Pfizer or Moderna, you're good to go.
Based on what I've seen online, it's protective (90%) vs. the now prevalent UK variant as well.
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Old 04-07-2021, 01:50 PM   #8679
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But in the end, I'll take whatever I'm offered. I don't have the luxury to do otherwise.
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Old 04-07-2021, 02:21 PM   #8680
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Based on what I've seen online, it's protective (90%) vs. the now prevalent UK variant as well.
Oh good stuff
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